siRNA, Anti-DSN1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46351WQ-2OMe)

The product SIRGT46351WQ-2OMe is a type of small interfering RNA (siRNA) that targets DSN1 gene and regulates the expression of gene. The siRNA interferes with the expression of DSN1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001145315.1
Alternative Names C20orf172; KNL3; MIS13; dJ469A13.2; hKNL-3
Related Diseases Arts Syndrome
Purification HPLC
Target Gene
Gene ID 79980
Uniprot ID Q9H410
Sub Cat Target Species Modification Scale  
SIRGT47351WQ-2F DSN1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48351WQ-2MOE DSN1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49351WQ-LNA DSN1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46351WQ-RB DSN1 Human Ribo-modified Inquiry
SIRGT47351WQ-BB DSN1 Human Backbone-modified Inquiry

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