siRNA, Anti-DTX1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06240WQ-2OMe)

The product SIRGT06240WQ-2OMe is a type of small interfering RNA (siRNA) that targets DTX1 gene and regulates the expression of gene. The siRNA interferes with the expression of DTX1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004416.2
Alternative Names hDx-1
Related Diseases Familial Pityriasis Rubra Pilaris
Purification HPLC
Target Gene
Gene ID 1840
Uniprot ID Q86Y01
Sub Cat Target Species Modification Scale  
SIRGT07240WQ-2F DTX1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08240WQ-2MOE DTX1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09240WQ-LNA DTX1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06240WQ-RB DTX1 Human Ribo-modified Inquiry
SIRGT07240WQ-BB DTX1 Human Backbone-modified Inquiry

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