siRNA, Anti-DVL2, 2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT06254WQ-2OMe)

The product SIRGT06254WQ-2OMe is a type of small interfering RNA (siRNA) that targets DVL2 gene and regulates the expression of gene. The siRNA interferes with the expression of DVL2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004422.2
Related Diseases Neural Tube Defects, Periosteal Osteogenic Sarcoma
Purification HPLC
Target Gene
Gene ID 1856
Uniprot ID O14641
Sub Cat Target Species Modification Scale  
SIRGT09254WQ-LNA DVL2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06254WQ-RB DVL2 Human Ribo-modified Inquiry
SIRGT07254WQ-BB DVL2 Human Backbone-modified Inquiry

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