siRNA, Anti-EBI3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31583WQ-2OMe)

The product SIRGT31583WQ-2OMe is a type of small interfering RNA (siRNA) that targets EBI3 gene and regulates the expression of gene. The siRNA interferes with the expression of EBI3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005755.2
Alternative Names IL-27B; IL27B; IL35B
Related Diseases Autoimmune Glomerulonephritis, Sialadenitis
Purification HPLC
Target Gene
Gene ID 10148
Uniprot ID Q14213
Sub Cat Target Species Modification Scale  
SIRGT32583WQ-2F EBI3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33583WQ-2MOE EBI3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34583WQ-LNA EBI3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31583WQ-RB EBI3 Human Ribo-modified Inquiry
SIRGT32583WQ-BB EBI3 Human Backbone-modified Inquiry

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