siRNA, Anti-ECI1, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06104WQ-2OMe)
The product SIRGT06104WQ-2OMe is a type of small interfering RNA (siRNA) that targets ECI1 gene and regulates the expression of gene. The siRNA interferes with the expression of ECI1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001178029.1; NM_001919.3 |
| Alternative Names | DCI |
| Related Diseases | Dysbaric Osteonecrosis, Transient Tic Disorder |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT08104WQ-2MOE | ECI1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT09104WQ-LNA | ECI1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT06104WQ-RB | ECI1 | Human | Ribo-modified | ||
| SIRGT07104WQ-BB | ECI1 | Human | Backbone-modified |