siRNA, Anti-EFCAB7, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT49946WQ-LNA)

The product SIRGT49946WQ-LNA is a type of small interfering RNA (siRNA) that targets EFCAB7 gene and regulates the expression of gene. The siRNA interferes with the expression of EFCAB7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032437.3
Related Diseases Ellis-Van Creveld Syndrome
Purification HPLC
Target Gene
Gene ID 84455
Uniprot ID A8K855
Sub Cat Target Species Modification Scale  
SIRGT96305WQ-2OMe Efcab7 Mouse 2ʹ-O-methyl (2'-OMe) Inquiry
SIRGT97305WQ-2F Efcab7 Mouse 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT96305WQ-RB Efcab7 Mouse Ribo-modified Inquiry
SIRGT47946WQ-BB EFCAB7 Human Backbone-modified Inquiry
SIRGT97305WQ-BB Efcab7 Mouse Backbone-modified Inquiry

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