siRNA, Anti-EFNB1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo-modified(CAT#: SIRGT06295WQ-2OMe)

The product SIRGT06295WQ-2OMe is a type of small interfering RNA (siRNA) that targets EFNB1 gene and regulates the expression of gene. The siRNA interferes with the expression of EFNB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004429.4
Alternative Names CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2
Related Diseases Craniofrontonasal Syndrome, Hemifacial Hyperplasia
Purification HPLC
Target Gene
Gene ID 1947
Uniprot ID P98172
Sub Cat Target Species Modification Scale  
SIRGT07295WQ-2F EFNB1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08295WQ-2MOE EFNB1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09295WQ-LNA EFNB1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06295WQ-RB EFNB1 Human Ribo-modified Inquiry

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