siRNA, Anti-EGR2, 2'-OMe-modified(CAT#: SIRGT06306WQ-2OMe)
The product SIRGT06306WQ-2OMe is a type of small interfering RNA (siRNA) that targets EGR2 gene and regulates the expression of gene. The siRNA interferes with the expression of EGR2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | 2ʹ-O-methyl (2'-OMe) |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_000399.4; NM_001136177.2; NM_001136178.1; NM_001136179.2; NM_001321037.1 |
| Alternative Names | AT591; CMT1D; CMT4E; KROX20 |
| Related Diseases | Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E) |
| Purification | HPLC |
