siRNA, Anti-EIF3E, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11348WQ-2OMe)

The product SIRGT11348WQ-2OMe is a type of small interfering RNA (siRNA) that targets EIF3E gene and regulates the expression of gene. The siRNA interferes with the expression of EIF3E gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001568.2
Alternative Names EIF3-P48; EIF3S6; INT6; eIF3-p46
Related Diseases Cadherin binding
Purification HPLC
Target Gene
Gene ID 3646
Uniprot ID P60228
Sub Cat Target Species Modification Scale  
SIRGT12348WQ-2F EIF3E Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13348WQ-2MOE EIF3E Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14348WQ-LNA EIF3E Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11348WQ-RB EIF3E Human Ribo-modified Inquiry
SIRGT12348WQ-BB EIF3E Human Backbone-modified Inquiry

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