siRNA, Anti-EIF5A, 2'-F/2'-OMe/LNA/Ribo-modified(CAT#: SIRGT06324WQ-2OMe)

The product SIRGT06324WQ-2OMe is a type of small interfering RNA (siRNA) that targets EIF5A gene and regulates the expression of gene. The siRNA interferes with the expression of EIF5A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001143760.1; NM_001143761.1; NM_001143762.1; NM_001970.4
Alternative Names EIF-5A; EIF5A1; eIF5AI
Related Diseases Human Immunodeficiency Virus Type 1, Nephronophthisis
Purification HPLC
Target Gene
Gene ID 1984
Uniprot ID P63241
Sub Cat Target Species Modification Scale  
SIRGT07324WQ-2F EIF5A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT09324WQ-LNA EIF5A Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06324WQ-RB EIF5A Human Ribo-modified Inquiry

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