siRNA, Anti-EMG1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31805WQ-2OMe)

The product SIRGT31805WQ-2OMe is a type of small interfering RNA (siRNA) that targets EMG1 gene and regulates the expression of gene. The siRNA interferes with the expression of EMG1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001320049.1; NM_006331.7
Alternative Names C2F; Grcc2f; NEP1
Related Diseases Bowen-Conradi Syndrome
Purification HPLC
Target Gene
Gene ID 10436
Uniprot ID Q92979
Sub Cat Target Species Modification Scale  
SIRGT32805WQ-2F EMG1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33805WQ-2MOE EMG1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34805WQ-LNA EMG1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31805WQ-RB EMG1 Human Ribo-modified Inquiry
SIRGT32805WQ-BB EMG1 Human Backbone-modified Inquiry

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