siRNA, Anti-EMP2, 2'-F/2'-OMe/2'-MOE/LNA/Backbone-modified(CAT#: SIRGT06345WQ-2OMe)

The product SIRGT06345WQ-2OMe is a type of small interfering RNA (siRNA) that targets EMP2 gene and regulates the expression of gene. The siRNA interferes with the expression of EMP2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001424.5
Alternative Names XMP
Related Diseases Genetic Steroid-Resistant Nephrotic Syndrome
Purification HPLC
Target Gene
Gene ID 2013
Uniprot ID P54851
Sub Cat Target Species Modification Scale  
SIRGT07345WQ-2F EMP2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08345WQ-2MOE EMP2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09345WQ-LNA EMP2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT07345WQ-BB EMP2 Human Backbone-modified Inquiry

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