siRNA, Anti-ERC1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT37676WQ-2F)
The product SIRGT37676WQ-2F is a type of small interfering RNA (siRNA) that targets ERC1 gene and regulates the expression of gene. The siRNA interferes with the expression of ERC1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-deoxy-2ʹ-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001301248.1 |
| Alternative Names | Cast2; ELKS; ERC-1; RAB6IP2 |
| Related Diseases | Differentiated Thyroid Carcinoma |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT39676WQ-LNA | ERC1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT81577WQ-2OMe | Erc1 | Mouse | 2ʹ-O-methyl (2'-OMe) | ||
| SIRGT82577WQ-2F | Erc1 | Mouse | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT83577WQ-2MOE | Erc1 | Mouse | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT84577WQ-LNA | Erc1 | Mouse | Locked Nucleic Acid (LNA) | ||
| SIRGT36676WQ-RB | ERC1 | Human | Ribo-modified | ||
| SIRGT81577WQ-RB | Erc1 | Mouse | Ribo-modified | ||
| SIRGT37676WQ-BB | ERC1 | Human | Backbone-modified | ||
| SIRGT82577WQ-BB | Erc1 | Mouse | Backbone-modified |
