siRNA, Anti-ERCC5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06398WQ-2OMe)

The product SIRGT06398WQ-2OMe is a type of small interfering RNA (siRNA) that targets ERCC5 gene and regulates the expression of gene. The siRNA interferes with the expression of ERCC5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000123.3
Alternative Names COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC
Related Diseases Xeroderma Pigmentosum
Purification HPLC
Target Gene
Gene ID 2073
Uniprot ID P28715
Sub Cat Target Species Modification Scale  
SIRGT07398WQ-2F ERCC5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08398WQ-2MOE ERCC5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09398WQ-LNA ERCC5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06398WQ-RB ERCC5 Human Ribo-modified Inquiry
SIRGT07398WQ-BB ERCC5 Human Backbone-modified Inquiry

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