siRNA, Anti-ERN2, 2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31937WQ-2OMe)

The product SIRGT31937WQ-2OMe is a type of small interfering RNA (siRNA) that targets ERN2 gene and regulates the expression of gene. The siRNA interferes with the expression of ERN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001308220.1; NM_033266.3
Alternative Names IRE1-BETA; IRE1b; IRE2p; hIRE2p
Related Diseases Orbital Granuloma
Purification HPLC
Target Gene
Gene ID 10595
Uniprot ID Q76MJ5
Sub Cat Target Species Modification Scale  
SIRGT33937WQ-2MOE ERN2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34937WQ-LNA ERN2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31937WQ-RB ERN2 Human Ribo-modified Inquiry
SIRGT32937WQ-BB ERN2 Human Backbone-modified Inquiry

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