siRNA, Anti-ERV3-1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06404WQ-2OMe)
The product SIRGT06404WQ-2OMe is a type of small interfering RNA (siRNA) that targets ERV3-1 gene and regulates the expression of gene. The siRNA interferes with the expression of ERV3-1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001007253.3 |
| Alternative Names | ERV-R; ERV3; ERVR; HERV-R; HERVR; envR |
| Related Diseases | Choriocarcinoma, Heart Block |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT07404WQ-2F | ERV3-1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT08404WQ-2MOE | ERV3-1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT06404WQ-RB | ERV3-1 | Human | Ribo-modified | ||
| SIRGT07404WQ-BB | ERV3-1 | Human | Backbone-modified |
