siRNA, Anti-ETV6, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06423WQ-2OMe)

The product SIRGT06423WQ-2OMe is a type of small interfering RNA (siRNA) that targets ETV6 gene and regulates the expression of gene. The siRNA interferes with the expression of ETV6 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001987.4
Alternative Names TEL; TEL/ABL; THC5
Related Diseases Thrombocytopenia 5, Hematologic Cancer
Purification HPLC
Target Gene
Gene ID 2120
Uniprot ID P41212
Sub Cat Target Species Modification Scale  
SIRGT07423WQ-2F ETV6 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08423WQ-2MOE ETV6 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09423WQ-LNA ETV6 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06423WQ-RB ETV6 Human Ribo-modified Inquiry
SIRGT07423WQ-BB ETV6 Human Backbone-modified Inquiry

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