siRNA, Anti-EVI2B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06427WQ-2OMe)

The product SIRGT06427WQ-2OMe is a type of small interfering RNA (siRNA) that targets EVI2B gene and regulates the expression of gene. The siRNA interferes with the expression of EVI2B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_006495.3
Alternative Names CD361; D17S376; EVDB
Related Diseases Restrictive Dermopathy
Purification HPLC
Target Gene
Gene ID 2124
Uniprot ID P34910
Sub Cat Target Species Modification Scale  
SIRGT07427WQ-2F EVI2B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08427WQ-2MOE EVI2B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09427WQ-LNA EVI2B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06427WQ-RB EVI2B Human Ribo-modified Inquiry
SIRGT07427WQ-BB EVI2B Human Backbone-modified Inquiry

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