siRNA, Anti-EVI5, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT26077WQ-2OMe)

The product SIRGT26077WQ-2OMe is a type of small interfering RNA (siRNA) that targets EVI5 gene and regulates the expression of gene. The siRNA interferes with the expression of EVI5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001308248.1; NM_001350197.1; NM_001350198.1; NM_005665.5
Alternative Names EVI-5; NB4S
Related Diseases Neuroblastoma
Purification HPLC
Target Gene
Gene ID 7813
Uniprot ID O60447
Sub Cat Target Species Modification Scale  
SIRGT27077WQ-2F EVI5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT29077WQ-LNA EVI5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT26077WQ-RB EVI5 Human Ribo-modified Inquiry
SIRGT27077WQ-BB EVI5 Human Backbone-modified Inquiry

Related Products