siRNA, Anti-FBXW5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT41162WQ-2OMe)

The product SIRGT41162WQ-2OMe is a type of small interfering RNA (siRNA) that targets FBXW5 gene and regulates the expression of gene. The siRNA interferes with the expression of FBXW5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_018998.3
Alternative Names Fbw5
Related Diseases Localized Chondrosarcoma
Purification HPLC
Target Gene
Gene ID 54461
Uniprot ID Q969U6
Sub Cat Target Species Modification Scale  
SIRGT42162WQ-2F FBXW5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT43162WQ-2MOE FBXW5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT44162WQ-LNA FBXW5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT41162WQ-RB FBXW5 Human Ribo-modified Inquiry
SIRGT42162WQ-BB FBXW5 Human Backbone-modified Inquiry

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