siRNA, Anti-FMO1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06573WQ-2OMe)
The product SIRGT06573WQ-2OMe is a type of small interfering RNA (siRNA) that targets FMO1 gene and regulates the expression of gene. The siRNA interferes with the expression of FMO1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| NCBI RefSeq | NM_001282692.1; NM_001282693.1; NM_001282694.1; NM_002021.2 |
| Related Diseases | Trimethylaminuria, Epiphyseal Dysplasia |
| Purification | HPLC |
| Sub Cat | Target | Species | Modification | Scale | |
|---|---|---|---|---|---|
| SIRGT07573WQ-2F | FMO1 | Human | 2ʹ-deoxy-2ʹ-fluoro (2'-F) | ||
| SIRGT08573WQ-2MOE | FMO1 | Human | 2'-O-methoxyethyl (2'-MOE) | ||
| SIRGT09573WQ-LNA | FMO1 | Human | Locked Nucleic Acid (LNA) | ||
| SIRGT06573WQ-RB | FMO1 | Human | Ribo-modified | ||
| SIRGT07573WQ-BB | FMO1 | Human | Backbone-modified |
