siRNA, Anti-FOXA3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11071WQ-2OMe)

The product SIRGT11071WQ-2OMe is a type of small interfering RNA (siRNA) that targets FOXA3 gene and regulates the expression of gene. The siRNA interferes with the expression of FOXA3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_004497.2
Alternative Names FKHH3; HNF3G; TCF3G
Related Diseases Maturity-Onset Diabetes Of The Young
Purification HPLC
Target Gene
Gene ID 3171
Uniprot ID P55318
Sub Cat Target Species Modification Scale  
SIRGT12071WQ-2F FOXA3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13071WQ-2MOE FOXA3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14071WQ-LNA FOXA3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11071WQ-RB FOXA3 Human Ribo-modified Inquiry
SIRGT12071WQ-BB FOXA3 Human Backbone-modified Inquiry

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