siRNA, Anti-FOXE3, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06552WQ-2OMe)

The product SIRGT06552WQ-2OMe is a type of small interfering RNA (siRNA) that targets FOXE3 gene and regulates the expression of gene. The siRNA interferes with the expression of FOXE3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_012186.2
Alternative Names AAT11; ASGD2; CTRCT34; FKHL12; FREAC8
Related Diseases Anterior Segment Dysgenesis
Purification HPLC
Target Gene
Gene ID 2301
Uniprot ID Q13461
Sub Cat Target Species Modification Scale  
SIRGT07552WQ-2F FOXE3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08552WQ-2MOE FOXE3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09552WQ-LNA FOXE3 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06552WQ-RB FOXE3 Human Ribo-modified Inquiry
SIRGT07552WQ-BB FOXE3 Human Backbone-modified Inquiry

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