siRNA, Anti-GABRA3, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06636WQ-2OMe)

The product SIRGT06636WQ-2OMe is a type of small interfering RNA (siRNA) that targets GABRA3 gene and regulates the expression of gene. The siRNA interferes with the expression of GABRA3 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000808.3
Related Diseases Thyrotoxic Periodic Paralysis, Angelman Syndrome
Purification HPLC
Target Gene
Gene ID 2556
Uniprot ID P34903
Sub Cat Target Species Modification Scale  
SIRGT07636WQ-2F GABRA3 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08636WQ-2MOE GABRA3 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06636WQ-RB GABRA3 Human Ribo-modified Inquiry
SIRGT07636WQ-BB GABRA3 Human Backbone-modified Inquiry

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