siRNA, Anti-GABRR2, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06650WQ-2OMe)

The product SIRGT06650WQ-2OMe is a type of small interfering RNA (siRNA) that targets GABRR2 gene and regulates the expression of gene. The siRNA interferes with the expression of GABRR2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002043.4
Related Diseases Alcohol dependence, General cognitive ability
Purification HPLC
Target Gene
Gene ID 2570
Uniprot ID P28476
Sub Cat Target Species Modification Scale  
SIRGT07650WQ-2F GABRR2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08650WQ-2MOE GABRR2 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09650WQ-LNA GABRR2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06650WQ-RB GABRR2 Human Ribo-modified Inquiry
SIRGT07650WQ-BB GABRR2 Human Backbone-modified Inquiry

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