siRNA, Anti-GAD1, 2'-F/2'-OMe/2'-MOE/LNA-modified(CAT#: SIRGT06651WQ-2OMe)

The product SIRGT06651WQ-2OMe is a type of small interfering RNA (siRNA) that targets GAD1 gene and regulates the expression of gene. The siRNA interferes with the expression of GAD1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000817.2; NM_013445.3
Alternative Names CPSQ1; GAD; SCP
Related Diseases Inherited Congenital Spastic Tetraplegia
Purification HPLC
Target Gene
Gene ID 2571
Uniprot ID Q99259
Sub Cat Target Species Modification Scale  
SIRGT07651WQ-2F GAD1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08651WQ-2MOE GAD1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09651WQ-LNA GAD1 Human Locked Nucleic Acid (LNA) Inquiry

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