siRNA, Anti-GADD45A, 2'-F/2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT06117WQ-2OMe)

The product SIRGT06117WQ-2OMe is a type of small interfering RNA (siRNA) that targets GADD45A gene and regulates the expression of gene. The siRNA interferes with the expression of GADD45A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001199741.1; NM_001199742.1; NM_001924.3
Alternative Names DDIT1; GADD45
Related Diseases Ataxia-Telangiectasia, Colorectal Cancer
Purification HPLC
Target Gene
Gene ID 1647
Uniprot ID P24522
Sub Cat Target Species Modification Scale  
SIRGT07117WQ-2F GADD45A Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT06117WQ-RB GADD45A Human Ribo-modified Inquiry
SIRGT07117WQ-BB GADD45A Human Backbone-modified Inquiry

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