siRNA, Anti-GADD45B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT11905WQ-2OMe)

The product SIRGT11905WQ-2OMe is a type of small interfering RNA (siRNA) that targets GADD45B gene and regulates the expression of gene. The siRNA interferes with the expression of GADD45B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_015675.3
Alternative Names GADD45BETA; MYD118
Related Diseases Lung Cancer, Hepatocellular Carcinoma
Purification HPLC
Target Gene
Gene ID 4616
Uniprot ID O75293
Sub Cat Target Species Modification Scale  
SIRGT12905WQ-2F GADD45B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT13905WQ-2MOE GADD45B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT14905WQ-LNA GADD45B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT11905WQ-RB GADD45B Human Ribo-modified Inquiry
SIRGT12905WQ-BB GADD45B Human Backbone-modified Inquiry

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