siRNA, Anti-GALE, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06655WQ-2OMe)

The product SIRGT06655WQ-2OMe is a type of small interfering RNA (siRNA) that targets GALE gene and regulates the expression of gene. The siRNA interferes with the expression of GALE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000403.3; NM_001008216.1; NM_001127621.1
Alternative Names SDR1E1
Related Diseases Generalized Galactose Epimerase Deficiency
Purification HPLC
Target Gene
Gene ID 2582
Uniprot ID Q14376
Sub Cat Target Species Modification Scale  
SIRGT07655WQ-2F GALE Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08655WQ-2MOE GALE Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06655WQ-RB GALE Human Ribo-modified Inquiry
SIRGT07655WQ-BB GALE Human Backbone-modified Inquiry

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