siRNA, Anti-GBE1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06681WQ-2OMe)

The product SIRGT06681WQ-2OMe is a type of small interfering RNA (siRNA) that targets GBE1 gene and regulates the expression of gene. The siRNA interferes with the expression of GBE1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000158.3
Alternative Names APBD; GBE; GSD4
Related Diseases Andersen's disease
Purification HPLC
Target Gene
Gene ID 2632
Uniprot ID Q04446
Sub Cat Target Species Modification Scale  
SIRGT07681WQ-2F GBE1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08681WQ-2MOE GBE1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09681WQ-LNA GBE1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06681WQ-RB GBE1 Human Ribo-modified Inquiry
SIRGT07681WQ-BB GBE1 Human Backbone-modified Inquiry

Related Products