siRNA, Anti-GBX2, 2'-F/2'-OMe/LNA/Ribo/Backbone-modified(CAT#: SIRGT06686WQ-2OMe)

The product SIRGT06686WQ-2OMe is a type of small interfering RNA (siRNA) that targets GBX2 gene and regulates the expression of gene. The siRNA interferes with the expression of GBX2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001301687.1; NM_001485.3
Related Diseases Colon Small Cell Carcinoma, Opitz-Gbbb Syndrome
Purification HPLC
Target Gene
Gene ID 2637
Uniprot ID P52951
Sub Cat Target Species Modification Scale  
SIRGT07686WQ-2F GBX2 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT09686WQ-LNA GBX2 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06686WQ-RB GBX2 Human Ribo-modified Inquiry
SIRGT07686WQ-BB GBX2 Human Backbone-modified Inquiry

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