siRNA, Anti-GHRHR, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06726WQ-2OMe)

The product SIRGT06726WQ-2OMe is a type of small interfering RNA (siRNA) that targets GHRHR gene and regulates the expression of gene. The siRNA interferes with the expression of GHRHR gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000823.3
Alternative Names GHRFR; GRFR; IGHD1B
Related Diseases Isolated growth hormone deficiency (IGHD)
Purification HPLC
Target Gene
Gene ID 2692
Uniprot ID Q02643
Sub Cat Target Species Modification Scale  
SIRGT07726WQ-2F GHRHR Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08726WQ-2MOE GHRHR Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09726WQ-LNA GHRHR Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06726WQ-RB GHRHR Human Ribo-modified Inquiry
SIRGT07726WQ-BB GHRHR Human Backbone-modified Inquiry

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