siRNA, Anti-GJA9, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46585WQ-2OMe)

The product SIRGT46585WQ-2OMe is a type of small interfering RNA (siRNA) that targets GJA9 gene and regulates the expression of gene. The siRNA interferes with the expression of GJA9 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_030772.4
Alternative Names CX58; CX59; GJA10
Related Diseases Deafness, Autosomal Dominant
Purification HPLC
Target Gene
Gene ID 81025
Uniprot ID P57773
Sub Cat Target Species Modification Scale  
SIRGT47585WQ-2F GJA9 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48585WQ-2MOE GJA9 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49585WQ-LNA GJA9 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46585WQ-RB GJA9 Human Ribo-modified Inquiry
SIRGT47585WQ-BB GJA9 Human Backbone-modified Inquiry

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