siRNA, Anti-GK, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06740WQ-2OMe)

The product SIRGT06740WQ-2OMe is a type of small interfering RNA (siRNA) that targets GK gene and regulates the expression of gene. The siRNA interferes with the expression of GK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000167.5; NM_001128127.2; NM_001205019.1; NM_203391.3
Alternative Names GK1; GKD
Related Diseases Glycerol kinase deficiency (GKD)
Purification HPLC
Target Gene
Gene ID 2710
Uniprot ID P32189
Sub Cat Target Species Modification Scale  
SIRGT07740WQ-2F GK Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08740WQ-2MOE GK Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09740WQ-LNA GK Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06740WQ-RB GK Human Ribo-modified Inquiry
SIRGT07740WQ-BB GK Human Backbone-modified Inquiry

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