siRNA, Anti-GNA12, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06770WQ-2OMe)

The product SIRGT06770WQ-2OMe is a type of small interfering RNA (siRNA) that targets GNA12 gene and regulates the expression of gene. The siRNA interferes with the expression of GNA12 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001282440.1; NM_001282441.1; NM_001293092.1; NM_007353.2
Alternative Names NNX3; RMP; gep
Related Diseases Gastrointestinal Defects, Immunodeficiency Syndrome
Purification HPLC
Target Gene
Gene ID 2768
Uniprot ID Q03113
Sub Cat Target Species Modification Scale  
SIRGT07770WQ-2F GNA12 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08770WQ-2MOE GNA12 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06770WQ-RB GNA12 Human Ribo-modified Inquiry
SIRGT07770WQ-BB GNA12 Human Backbone-modified Inquiry

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