siRNA, Anti-GNB1, 2'-F/2'-OMe/2'-MOE/Ribo/Backbone-modified(CAT#: SIRGT06782WQ-2OMe)

The product SIRGT06782WQ-2OMe is a type of small interfering RNA (siRNA) that targets GNB1 gene and regulates the expression of gene. The siRNA interferes with the expression of GNB1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001282538.1; NM_001282539.1; NM_002074.4
Alternative Names MRD42
Related Diseases Autosomal Dominant Congenital Stationary Night Blindness
Purification HPLC
Target Gene
Gene ID 2782
Uniprot ID P62873
Sub Cat Target Species Modification Scale  
SIRGT07782WQ-2F GNB1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08782WQ-2MOE GNB1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT06782WQ-RB GNB1 Human Ribo-modified Inquiry
SIRGT07782WQ-BB GNB1 Human Backbone-modified Inquiry

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