siRNA, Anti-GNPDA1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31471WQ-2OMe)

The product SIRGT31471WQ-2OMe is a type of small interfering RNA (siRNA) that targets GNPDA1 gene and regulates the expression of gene. The siRNA interferes with the expression of GNPDA1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005471.4
Alternative Names GNP1; GNPDA; GNPI; GPI; HLN
Related Diseases Griscelli Syndrome, Type 3
Purification HPLC
Target Gene
Gene ID 10007
Uniprot ID P46926
Sub Cat Target Species Modification Scale  
SIRGT32471WQ-2F GNPDA1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33471WQ-2MOE GNPDA1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34471WQ-LNA GNPDA1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31471WQ-RB GNPDA1 Human Ribo-modified Inquiry
SIRGT32471WQ-BB GNPDA1 Human Backbone-modified Inquiry

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