siRNA, Anti-GON7, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46959WQ-2OMe)

The product SIRGT46959WQ-2OMe is a type of small interfering RNA (siRNA) that targets GON7 gene and regulates the expression of gene. The siRNA interferes with the expression of GON7 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_032490.4
Alternative Names C14orf142; PNAS-127
Related Diseases Galloway-Mowat Syndrome
Purification HPLC
Target Gene
Gene ID 84520
Uniprot ID Q9BXV9
Sub Cat Target Species Modification Scale  
SIRGT47959WQ-2F GON7 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48959WQ-2MOE GON7 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49959WQ-LNA GON7 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46959WQ-RB GON7 Human Ribo-modified Inquiry
SIRGT47959WQ-BB GON7 Human Backbone-modified Inquiry

Related Products