siRNA, Anti-GPA33, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT31646WQ-2OMe)

The product SIRGT31646WQ-2OMe is a type of small interfering RNA (siRNA) that targets GPA33 gene and regulates the expression of gene. The siRNA interferes with the expression of GPA33 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005814.2
Alternative Names A33
Related Diseases Foodborne Botulism, Wound Botulism
Purification HPLC
Target Gene
Gene ID 10223
Uniprot ID Q99795
Sub Cat Target Species Modification Scale  
SIRGT32646WQ-2F GPA33 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT33646WQ-2MOE GPA33 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT34646WQ-LNA GPA33 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT31646WQ-RB GPA33 Human Ribo-modified Inquiry
SIRGT32646WQ-BB GPA33 Human Backbone-modified Inquiry

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