siRNA, Anti-GPC4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06506WQ-2OMe)

The product SIRGT06506WQ-2OMe is a type of small interfering RNA (siRNA) that targets GPC4 gene and regulates the expression of gene. The siRNA interferes with the expression of GPC4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001448.2
Alternative Names K-glypican
Related Diseases Simpson-Golabi-Behmel Syndrome
Purification HPLC
Target Gene
Gene ID 2239
Uniprot ID O75487
Sub Cat Target Species Modification Scale  
SIRGT07506WQ-2F GPC4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08506WQ-2MOE GPC4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09506WQ-LNA GPC4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06506WQ-RB GPC4 Human Ribo-modified Inquiry
SIRGT07506WQ-BB GPC4 Human Backbone-modified Inquiry

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