siRNA, Anti-GPR137B, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT21675WQ-2OMe)

The product SIRGT21675WQ-2OMe is a type of small interfering RNA (siRNA) that targets GPR137B gene and regulates the expression of gene. The siRNA interferes with the expression of GPR137B gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_003272.3
Alternative Names TM7SF1
Related Diseases Spinal Muscular Atrophy
Purification HPLC
Target Gene
Gene ID 7107
Uniprot ID O60478
Sub Cat Target Species Modification Scale  
SIRGT22675WQ-2F GPR137B Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT23675WQ-2MOE GPR137B Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT24675WQ-LNA GPR137B Human Locked Nucleic Acid (LNA) Inquiry
SIRGT21675WQ-RB GPR137B Human Ribo-modified Inquiry
SIRGT22675WQ-BB GPR137B Human Backbone-modified Inquiry

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