siRNA, Anti-GRK5, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06854WQ-2OMe)

The product SIRGT06854WQ-2OMe is a type of small interfering RNA (siRNA) that targets GRK5 gene and regulates the expression of gene. The siRNA interferes with the expression of GRK5 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005308.2
Alternative Names GPRK5
Related Diseases Systolic Heart Failure, Asthma
Purification HPLC
Target Gene
Gene ID 2869
Uniprot ID P34947
Sub Cat Target Species Modification Scale  
SIRGT07854WQ-2F GRK5 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08854WQ-2MOE GRK5 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09854WQ-LNA GRK5 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06854WQ-RB GRK5 Human Ribo-modified Inquiry
SIRGT07854WQ-BB GRK5 Human Backbone-modified Inquiry

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