siRNA, Anti-GRM1, 2'-F/2'-OMe/Ribo/Backbone-modified(CAT#: SIRGT06890WQ-2OMe)

The product SIRGT06890WQ-2OMe is a type of small interfering RNA (siRNA) that targets GRM1 gene and regulates the expression of gene. The siRNA interferes with the expression of GRM1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001278064.1; NM_001278065.1; NM_001278066.1; NM_001278067.1
Alternative Names GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13
Related Diseases Schizophrenia, Bipolar disorder, Depression
Purification HPLC
Target Gene
Gene ID 2911
Uniprot ID Q13255
Sub Cat Target Species Modification Scale  
SIRGT07890WQ-2F GRM1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT06890WQ-RB GRM1 Human Ribo-modified Inquiry
SIRGT07890WQ-BB GRM1 Human Backbone-modified Inquiry

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