siRNA, Anti-GRPEL1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT46482WQ-2OMe)

The product SIRGT46482WQ-2OMe is a type of small interfering RNA (siRNA) that targets GRPEL1 gene and regulates the expression of gene. The siRNA interferes with the expression of GRPEL1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_025196.3
Alternative Names GrpE; HMGE; mt-GrpE#1
Related Diseases Human Monocytic Ehrlichiosis
Purification HPLC
Target Gene
Gene ID 80273
Uniprot ID Q9HAV7
Sub Cat Target Species Modification Scale  
SIRGT47482WQ-2F GRPEL1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT48482WQ-2MOE GRPEL1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT49482WQ-LNA GRPEL1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT46482WQ-RB GRPEL1 Human Ribo-modified Inquiry
SIRGT47482WQ-BB GRPEL1 Human Backbone-modified Inquiry

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