siRNA, Anti-GTF2E1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06927WQ-2OMe)

The product SIRGT06927WQ-2OMe is a type of small interfering RNA (siRNA) that targets GTF2E1 gene and regulates the expression of gene. The siRNA interferes with the expression of GTF2E1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_005513.2
Alternative Names FE; TF2E1; TFIIE-A
Related Diseases Trichothiodystrophy
Purification HPLC
Target Gene
Gene ID 2960
Uniprot ID P29083
Sub Cat Target Species Modification Scale  
SIRGT07927WQ-2F GTF2E1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08927WQ-2MOE GTF2E1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09927WQ-LNA GTF2E1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06927WQ-RB GTF2E1 Human Ribo-modified Inquiry
SIRGT07927WQ-BB GTF2E1 Human Backbone-modified Inquiry

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