siRNA, Anti-GTF2H4, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06933WQ-2OMe)

The product SIRGT06933WQ-2OMe is a type of small interfering RNA (siRNA) that targets GTF2H4 gene and regulates the expression of gene. The siRNA interferes with the expression of GTF2H4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001517.4
Alternative Names P52; TFB2; TFIIH
Related Diseases Cockayne Syndrome
Purification HPLC
Target Gene
Gene ID 2968
Uniprot ID Q92759
Sub Cat Target Species Modification Scale  
SIRGT07933WQ-2F GTF2H4 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08933WQ-2MOE GTF2H4 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09933WQ-LNA GTF2H4 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06933WQ-RB GTF2H4 Human Ribo-modified Inquiry
SIRGT07933WQ-BB GTF2H4 Human Backbone-modified Inquiry

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