siRNA, Anti-GYS1, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06954WQ-2OMe)

The product SIRGT06954WQ-2OMe is a type of small interfering RNA (siRNA) that targets GYS1 gene and regulates the expression of gene. The siRNA interferes with the expression of GYS1 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_001161587.1; NM_002103.4
Alternative Names GSY; GYS
Related Diseases Muscle glycogen storage disease
Purification HPLC
Target Gene
Gene ID 2997
Uniprot ID P13807
Sub Cat Target Species Modification Scale  
SIRGT07954WQ-2F GYS1 Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08954WQ-2MOE GYS1 Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09954WQ-LNA GYS1 Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06954WQ-RB GYS1 Human Ribo-modified Inquiry
SIRGT07954WQ-BB GYS1 Human Backbone-modified Inquiry

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