siRNA, Anti-GZMK, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06960WQ-2OMe)

The product SIRGT06960WQ-2OMe is a type of small interfering RNA (siRNA) that targets GZMK gene and regulates the expression of gene. The siRNA interferes with the expression of GZMK gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_002104.2
Alternative Names TRYP2
Related Diseases T-Cell Large Granular Lymphocyte Leukemia
Purification HPLC
Target Gene
Gene ID 3003
Uniprot ID P49863
Sub Cat Target Species Modification Scale  
SIRGT07960WQ-2F GZMK Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08960WQ-2MOE GZMK Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09960WQ-LNA GZMK Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06960WQ-RB GZMK Human Ribo-modified Inquiry
SIRGT07960WQ-BB GZMK Human Backbone-modified Inquiry

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