siRNA, Anti-HBD, 2'-F/2'-OMe/2'-MOE/LNA/Ribo/Backbone-modified(CAT#: SIRGT06991WQ-2OMe)

The product SIRGT06991WQ-2OMe is a type of small interfering RNA (siRNA) that targets HBD gene and regulates the expression of gene. The siRNA interferes with the expression of HBD gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2ʹ-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.

Specifications
NCBI RefSeq NM_000519.3
Related Diseases Hemoglobin Lepore-Beta-Thalassemia Syndrome
Purification HPLC
Target Gene
Gene ID 3045
Uniprot ID P02042
Sub Cat Target Species Modification Scale  
SIRGT07991WQ-2F HBD Human 2ʹ-deoxy-2ʹ-fluoro (2'-F) Inquiry
SIRGT08991WQ-2MOE HBD Human 2'-O-methoxyethyl (2'-MOE) Inquiry
SIRGT09991WQ-LNA HBD Human Locked Nucleic Acid (LNA) Inquiry
SIRGT06991WQ-RB HBD Human Ribo-modified Inquiry
SIRGT07991WQ-BB HBD Human Backbone-modified Inquiry

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