siRNA, Anti-HELLS, Backbone-modified(CAT#: SIRGT12009WQ-BB)
The product SIRGT12009WQ-BB is a type of small interfering RNA (siRNA) that targets HELLS gene and regulates the expression of gene. The siRNA interferes with the expression of HELLS gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with backbone modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.
| Specifications | |
|---|---|
| Modification | Backbone-modified |
| Scale | 20/50/100/200 nmole |
| NCBI RefSeq | NM_001289067.1; NM_001289068.1; NM_001289069.1; NM_001289070.1; NM_001289071.1; NM_001289072.1; NM_001289073.1; NM_001289074.1; NM_001289075.1; NM_018063.4 |
| Alternative Names | ICF4; LSH; Nbla10143; PASG; SMARCA6 |
| Related Diseases | Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome |
| Purification | HPLC |
